Gadopentetate monomeglumine 99% CAS NO.92923-57-4

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetate monomeglumine

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Gadopentetic acid is one of the trade names for a gadolinium -basedMRI contrast agent, usually administered as a salt of a complex of gadolinium with DTPA (diethylenetriaminepentacetate ) with the chemical formula A₂[Gd(DTPA)(H₂O)]; when cation A is the protonated form of theamino sugar meglumine the salt goes under the name "Gadopentetate dimeglumine". It was described in 1981 and introduced as the first MRI contrast agent in 1987. It is used to assist imaging of blood vessels and of inflamed or diseased tissue where the blood vessels become 'leaky'. It is often used when viewing intracranial lesions with abnormal vascularity or abnormalities in the blood–brain barrier. It is usually injected intravenously. Gd-DTPA is classed as an acyclic, ionic gadolinium contrast medium. Its paramagnetic property reduces the T1relaxation time (and to some extent the T2 and T2* relaxation times) inNMR, which is the source of its clinical utility.

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetate monomeglumine

Gadopentetic acid

Clinical data
AHFS/Drugs.com	Consumer Drug Information
Pregnancy cat.
Legal status
Pharmacokinetic data
Half-life	Distribution half life 12 minutes, elimination half 100 minutes
Identifiers
CAS number	86050-77-3
ATC code	V08CA01
PubChem	CID 55466
DrugBank	DB00789
ChemSpider	50087
UNII	RH248G8V27
KEGG	D01707
ChEBI	CHEBI:31797
ChEMBL	CHEMBL1200431
Chemical data
Formula	C28H54GdN5O20

CAS No.:	92923-57-4
Name:	Gadopentetate monomeglumine
Molecular Structure:
Formula:	C14H20GdN3O10.C7H17NO5
Molecular Weight:	742.79
Synonyms:	Gadolinate(2-), (N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, dihydrogen, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1);Meglumine-gadolinium-edta;Meglumine gadopentate;