Vecuronium bromide 99.9% CAS NO.50700-72-6

Vecuronium bromide,

Vecuronium bromide

Vecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Although vecuronium bromide is often thought of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent. It is commercially available as ampoules containing 4 or 10 mg of the drug in powder form which needs to be dissolved in distilled water prior to administration to the patient.

Vecuronium bromide

Vecuronium bromide

Vecuronium bromide

Systematic (IUPAC) name
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17S)- 17-acetyloxy-10,13-dimethyl-16-(1-methyl-3,4, 5,6-tetrahydro-2H-pyridin-1-yl)-2-(1-piperidyl)- 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro- 1H-cyclopenta[a]phenanthren-3-yl] acetate
Clinical data
AHFS/Drugs.com	monograph
Pregnancy cat.	C (US)
Legal status	-only (US)
Routes	Intravenous
Pharmacokinetic data
Bioavailability	100% (IV)
Metabolism	liver 30%
Half-life	51–80 minutes (longer with renal failure)
Excretion	Fecal (40-75%)renal (30% as unchanged drug metabolites)
Identifiers
CAS number	50700-72-6
ATC code	M03AC03
PubChem	CID 39765
UNII	7E4PHP5N1D
ChEMBL	CHEMBL1201219
Chemical data
Formula	C34H57N2O4+
Mol. mass	557.827 g/mol