China (Mainland)
best Butenafine hydrochloride assay 99% CAS NO.101827-46-7
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
99%(1-10)Kilogram
- Product Details
Keywords
- Butenafine hydrochloride
- cas：101827-46-7
- Butenafine hydrochloride
Quick Details
- ProName: best Butenafine hydrochloride assay 99...
- CasNo: 101827-46-7
- Molecular Formula: C23H27N.HCl;C23H28ClN
- Appearance: white powder
- Application: intermediate
- DeliveryTime: 3days
- PackAge: 25kg/drum，10kg/drum
- Port: china（beijing，shanghai，qingdao）
- ProductionCapacity: 15 Kilogram/Day
- Purity: 99%
- Storage: 20-25℃
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- Moisture Content: 0.1%
- Impurity: 0.03%
- assay: 99.9
- Standard: complies to EP9, USP39
Superiority
Pharmacology[edit]
Butenafine hydrochloride is an odorless white crystalline powder that is freely soluble in methanol, ethanol, and chloroform, and slightly soluble in water.
Like the allylamine antifungals, butenafine works by inhibiting the synthesis of ergosterol by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak out.
CERTIFICATE OF ANALYSIS
|
Product name |
Butenafine HCl |
Batch No |
17091901 |
|
Mfg.Date |
2017-09-19 |
Exp.Date |
2019-09 |
|
Report Date |
2017-09-29 |
Quantity |
100kg |
|
Items |
Standard |
Test results |
|
Description |
White crystalline powder |
Conforms |
|
It is very soluble in formic acid, freely soluble in methanol, ethanol(99.5),slightly soluble in water. The PH of water solution obtained by dissolving of 0.2 g of Butenafine hydrochloride in 100ml of water by warming, and cooling, is between 3.0 and 4.0。 |
Conforms |
|
|
Meltin poine |
About 214℃(with decomposition) |
212℃ |
|
Identification |
1.Both spectra exhibit similar intensities of absorption at the same wavelengths. |
Conforms |
|
2.Both spectra exhibit similar intensities of absorption at the same wave numbers. |
Conforms |
|
|
3.For chloride |
Conforms |
|
|
Related substances: |
Relative retention time 0.16 impurity<0.03% |
N.D. |
|
Any other impurity≤0.1% |
0.09% |
|
|
Total impurity≤1.0% |
0.33% |
|
|
Heavy metals |
Not more than 10ppm |
Conforms |
|
Loss on drying |
Not more than 0.1% |
0.08% |
|
Residue on ignition |
Not more than 0.10% |
0.07% |
|
Assay |
Not less than 99.0-101.0% |
99.5% |
|
Conclusion |
Conforms to JP16. |
|
Details
CERTIFICATE OF ANALYSIS
|
Product name |
Butenafine HCl |
Batch No |
17091901 |
|
Mfg.Date |
2017-09-19 |
Exp.Date |
2019-09 |
|
Report Date |
2017-09-29 |
Quantity |
100kg |
|
Items |
Standard |
Test results |
|
Description |
White crystalline powder |
Conforms |
|
It is very soluble in formic acid, freely soluble in methanol, ethanol(99.5),slightly soluble in water. The PH of water solution obtained by dissolving of 0.2 g of Butenafine hydrochloride in 100ml of water by warming, and cooling, is between 3.0 and 4.0。 |
Conforms |
|
|
Meltin poine |
About 214℃(with decomposition) |
212℃ |
|
Identification |
1.Both spectra exhibit similar intensities of absorption at the same wavelengths. |
Conforms |
|
2.Both spectra exhibit similar intensities of absorption at the same wave numbers. |
Conforms |
|
|
3.For chloride |
Conforms |
|
|
Related substances: |
Relative retention time 0.16 impurity<0.03% |
N.D. |
|
Any other impurity≤0.1% |
0.09% |
|
|
Total impurity≤1.0% |
0.33% |
|
|
Heavy metals |
Not more than 10ppm |
Conforms |
|
Loss on drying |
Not more than 0.1% |
0.08% |
|
Residue on ignition |
Not more than 0.10% |
0.07% |
|
Assay |
Not less than 99.0-101.0% |
99.5% |
|
Conclusion |
Conforms to JP16. |
|