China (Mainland)
Donepezil hydrochloride CAS NO.120011-70-3
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
99%(1-20)Kilogram
- Product Details
Keywords
- Donepezil hydrochloride cas:120011-70-3
- Donepezil hcl
- Donepezil HCL
Quick Details
- ProName: Donepezil hydrochloride
- CasNo: 120011-70-3
- Molecular Formula: C24H30ClNO3
- Appearance: powder
- Application: cas:120011-70-3 Pharmaceutical interm...
- DeliveryTime: According to the contract requirements
- PackAge: fiber can/aluminum foil bag
- Port: china（qingdao/beijing/shanghai/hangzho...
- ProductionCapacity: 75 Kilogram/Month
- Purity: 99.0%
- Storage: 20-25℃
- Transportation: by air/by sea
- LimitNum: 1 Kilogram
- Moisture Content: 0.1
- Impurity: 0.03%
- Grade: Pharma Grade
- assay: 99%
- Standard: EP9, USP40
- Sodium chloride: 0.1%
Superiority
Donepezil, marketed under the trade name Aricept by its developerEisai and partner Pfizer, and also marketed under the brand name DONEPby Alkem Pentacare, is a centrally acting reversibleacetylcholinesterase inhibitor.[1] Its main therapeutic use is in thepalliative treatment of Alzheimer's disease.[2] Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood–brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.
Details
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|
|---|---|
| Systematic (IUPAC) name | |
| (RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one | |
| Clinical data | |
| Trade names | Aricept |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a697032 |
| Pregnancy cat. | C |
| Legal status | Prescription only |
| Routes | Oral tablet, 5,10 & 23mg |
| Pharmacokinetic data | |
| Bioavailability | 100 (%) |
| Protein binding | 96% |
| Half-life | 70 hours |
| Excretion | 0,11-0,13 (l/h/kg) |
| Identifiers | |
| CAS number |
120014-06-4  |
| ATC code | N06DA02 |
| PubChem | CID 3152 |
| DrugBank | DB00843 |
| ChemSpider |
3040 |
| UNII |
8SSC91326P |
| KEGG |
D07869 |
| ChEBI |
CHEBI:53289 |
| ChEMBL |
CHEMBL502 |
| Chemical data | |
| Formula | C24H29NO3 |
| Mol. mass | 379.492 g/mol |