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Home > Products >  Donepezil hydrochloride

Donepezil hydrochloride CAS NO.120011-70-3

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  • FOB Price: USD 1 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,Western Union,MoneyGram,Other
  • Available Specifications:

    99%(1-20)Kilogram

  • Product Details

Keywords

  • Donepezil hydrochloride cas:120011-70-3
  • Donepezil hcl
  • Donepezil HCL

Quick Details

  • ProName: Donepezil hydrochloride
  • CasNo: 120011-70-3
  • Molecular Formula: C24H30ClNO3
  • Appearance: powder
  • Application: cas:120011-70-3 Pharmaceutical interm...
  • DeliveryTime: According to the contract requirements
  • PackAge: fiber can/aluminum foil bag
  • Port: china(qingdao/beijing/shanghai/hangzho...
  • ProductionCapacity: 75 Kilogram/Month
  • Purity: 99.0%
  • Storage: 20-25℃
  • Transportation: by air/by sea
  • LimitNum: 1 Kilogram
  • Moisture Content: 0.1
  • Impurity: 0.03%
  • Grade: Pharma Grade
  • assay: 99%
  • Standard: EP9, USP40
  • Sodium chloride: 0.1%

Superiority

donepezil, marketed under the trade name aricept by its developereisai and partner pfizer, and also marketed under the brand name donepby alkem pentacare, is a centrally acting reversibleacetylcholinesterase inhibitor.[1] its main therapeutic use is in thepalliative treatment of alzheimer's disease.[2] common side effects include gastrointestinal upset. it has an oral bioavailability of 100% and easily crosses the blood–brain barrier. because it has a biological half-life of about 70 hours, it can be taken once a day.

Details

Donepezil
Systematic (IUPAC) name
(RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one
Clinical data
Trade names Aricept
AHFS/Drugs.com monograph
MedlinePlus a697032
Pregnancy cat. C
Legal status  Prescription only
Routes Oral tablet, 5,10 & 23mg
Pharmacokinetic data
Bioavailability 100 (%)
Protein binding 96%
Half-life 70 hours
Excretion 0,11-0,13 (l/h/kg)
Identifiers
CAS number 120014-06-4 Yes
ATC code N06DA02
PubChem CID 3152
DrugBank DB00843
ChemSpider 3040 Yes
UNII 8SSC91326P Yes
KEGG D07869 Yes
ChEBI CHEBI:53289 Yes
ChEMBL CHEMBL502 Yes
Chemical data
Formula C24H29NO3 
Mol. mass 379.492 g/mol

 

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